Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 | |
SETBP1 | Q9Y6X0 | SET binding protein 1 | 1.00 | 0.503 | 0.808 | |
SH2B3 | Q9UQQ2 | SH2B adaptor protein 3 | 1.0E-04 | 0.527 | 0.692 | |
RUNX1 | Q01196 | RUNX family transcription factor 1 | Transcription factor | 0.65 | 0.425 | 0.808 |
CBL | P22681 | Cbl proto-oncogene | Enzyme | 6.1E-04 | 0.527 | 0.769 |
JAK3 | P52333 | Janus kinase 3 | Kinase | 5.9E-06 | 0.505 | 0.731 |
GATA2 | P23769 | GATA binding protein 2 | 0.98 | 0.496 | 0.654 | |
RRAS2 | P62070 | RAS related 2 | Enzyme modulator | 0.97 | 0.656 | 0.500 |
ASXL1 | Q8IXJ9 | ASXL transcriptional regulator 1 | 1.3E-14 | 0.482 | 0.808 | |
RRAS | P10301 | RAS related | Enzyme modulator | 4.7E-03 | 0.543 | 0.808 |
RAC2 | P15153 | Rac family small GTPase 2 | Enzyme modulator | 0.97 | 0.556 | 0.731 |
ARHGAP26 | Q9UNA1 | Rho GTPase activating protein 26 | Enzyme modulator | 1.00 | 0.656 | 0.500 |
ZRSR2 | Q15696 | zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 | Nucleic acid binding | 1.00 | 0.751 | 0.231 |