Disease: Refractory anaemia with excess blasts
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKAP12 Q02952 A-kinase anchoring protein 12 3.6E-02 0.566 0.615
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MOGS Q13724 mannosyl-oligosaccharide glucosidase 5.8E-11 0.626 0.731
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
THPO P40225 thrombopoietin 0.20 0.513 0.692
THY1 P04216 Thy-1 cell surface antigen 5.0E-02 0.496 0.808
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
U2AF1L5 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 like 5 0.769 0.308