Disease: Histiocytosis, Langerhans-Cell
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KITLG P21583 KIT ligand 0.85 0.473 0.885
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962