Disease: Sezary Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 1.00 0.486 0.846
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
EBI3 Q14213 Epstein-Barr virus induced 3 Signaling 0.11 0.474 0.808
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
IL2RG P31785 interleukin 2 receptor subunit gamma Signaling 0.99 0.535 0.769
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MIR223 microRNA 223 0.433 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808