Disease: Malignant neoplasm of breast
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
CENPF P49454 centromere protein F 1.9E-36 0.601 0.654
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
ROBO1 Q9Y6N7 roundabout guidance receptor 1 7.3E-16 0.535 0.731
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
SPATA18 Q8TC71 spermatogenesis associated 18 1.0E-13 0.805 0.115
ITSN2 Q9NZM3 intersectin 2 Enzyme modulator 9.8E-13 0.711 0.423
SULT1A1 P50225 sulfotransferase family 1A member 1 3.0E-11 0.554 0.769
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PDZK1 Q5T2W1 PDZ domain containing 1 1.2E-09 0.650 0.654
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
ETV4 P43268 ETS variant transcription factor 4 Transcription factor 2.9E-08 0.545 0.500
HOXB13 Q92826 homeobox B13 3.7E-08 0.573 0.462
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923