TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
VEGFA |
P15692
|
vascular endothelial growth factor A
|
Signaling
|
2.4E-05 |
0.266 |
0.923 |
TGFB1 |
P01137
|
transforming growth factor beta 1
|
Signaling
|
3.7E-02 |
0.287 |
0.962 |
BCL2 |
P10415
|
BCL2 apoptosis regulator
|
Signaling
|
0.56 |
0.291 |
0.885 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
EGFR |
P00533
|
epidermal growth factor receptor
|
Kinase
|
0.37 |
0.295 |
0.885 |
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
CXCL8 |
P10145
|
C-X-C motif chemokine ligand 8
|
Signaling
|
2.7E-04 |
0.310 |
0.962 |
PTGS2 |
P35354
|
prostaglandin-endoperoxide synthase 2
|
Enzyme
|
1.00 |
0.314 |
0.962 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
STAT3 |
P40763
|
signal transducer and activator of transcription 3
|
Nucleic acid binding
|
1.00 |
0.320 |
0.923 |
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
ACE |
P12821
|
angiotensin I converting enzyme
|
Enzyme
|
1.0E-37 |
0.328 |
0.923 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
CCND1 |
P24385
|
cyclin D1
|
Enzyme modulator
|
0.89 |
0.344 |
0.923 |
MYC |
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
1.00 |
0.344 |
0.923 |
EGF |
P01133
|
epidermal growth factor
|
|
8.5E-17 |
0.357 |
0.923 |
APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
NOS3 |
P29474
|
nitric oxide synthase 3
|
|
6.7E-07 |
0.378 |
0.885 |
SOD2 |
P04179
|
superoxide dismutase 2
|
Enzyme
|
0.15 |
0.379 |
0.923 |
MET |
P08581
|
MET proto-oncogene, receptor tyrosine kinase
|
Kinase
|
0.97 |
0.380 |
0.846 |
ESR2 |
Q92731
|
estrogen receptor 2
|
Nuclear receptor
|
4.5E-08 |
0.400 |
0.923 |
DNMT1 |
P26358
|
DNA methyltransferase 1
|
Epigenetic regulator
|
1.00 |
0.406 |
0.885 |
CYP19A1 |
P11511
|
cytochrome P450 family 19 subfamily A member 1
|
Enzyme
|
1.7E-05 |
0.410 |
0.885 |