Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
CST1 P01037 cystatin SN 3.4E-08 0.659 0.577
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
UMPS P11172 uridine monophosphate synthetase 1.1E-04 0.584 0.615
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGFBP7 Q16270 insulin like growth factor binding protein 7 1.3E-03 0.476 0.769
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846