Disease: Colorectal Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962