Disease: 2-3 toe syndactyly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ACSL4 O60488 acyl-CoA synthetase long chain family member 4 Enzyme 0.98 0.561 0.769
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMPR1B O00238 bone morphogenetic protein receptor type 1B Kinase 1.00 0.573 0.615
CEP55 Q53EZ4 centrosomal protein 55 2.0E-12 0.534 0.731
DMD P11532 dystrophin 1.00 0.423 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HCFC1 P51610 host cell factor C1 1.00 0.601 0.692
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
MEIS2 O14770 Meis homeobox 2 Enzyme 1.00 0.601 0.808
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
NOG Q13253 noggin 0.89 0.518 0.731
PAK3 O75914 p21 (RAC1) activated kinase 3 Kinase 0.99 0.569 0.731
PTCH1 Q13635 patched 1 1.00 0.398 0.885
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RBPJ Q06330 recombination signal binding protein for immunoglobulin kappa J region Nucleic acid binding 1.00 0.518 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
SALL1 Q9NSC2 spalt like transcription factor 1 Transcription factor 1.00 0.539 0.808
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOX5 P35711 SRY-box transcription factor 5 1.00 0.545 0.769