Disease: Cleft palate, isolated
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IRF6 O14896 interferon regulatory factor 6 Transcription factor 1.00 0.486 0.769
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
SPRY2 O43597 sprouty RTK signaling antagonist 2 Signaling 0.97 0.554 0.654
ALX3 O95076 ALX homeobox 3 1.9E-02 0.578 0.692
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGF3 P11487 fibroblast growth factor 3 Signaling 9.3E-05 0.505 0.808
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
PAX3 P23760 paired box 3 0.24 0.481 0.769
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
RYK P34925 receptor like tyrosine kinase Kinase 0.99 0.705 0.423
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885