Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
S100B | P04271 | S100 calcium binding protein B | Calcium-binding protein | 4.4E-02 | 0.383 | 0.923 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
CCN2 | P29279 | cellular communication network factor 2 | Signaling | 5.0E-04 | 0.399 | 0.846 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
CD38 | P28907 | CD38 molecule | Enzyme | 2.3E-06 | 0.407 | 0.885 |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |