Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
AFP | P02771 | alpha fetoprotein | Transporter | 1.1E-11 | 0.429 | 0.885 |
DKK1 | O94907 | dickkopf WNT signaling pathway inhibitor 1 | 0.17 | 0.439 | 0.885 | |
ERCC8 | Q13216 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit | 2.8E-15 | 0.551 | 0.885 | |
FOLR1 | P15328 | folate receptor alpha | 0.13 | 0.522 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
IL37 | Q9NZH6 | interleukin 37 | 1.2E-04 | 0.459 | 0.846 | |
SYNE1 | Q8NF91 | spectrin repeat containing nuclear envelope protein 1 | 3.2E-52 | 0.511 | 0.846 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
ITPR1 | Q14643 | inositol 1,4,5-trisphosphate receptor type 1 | Ion channel | 1.00 | 0.534 | 0.846 |
WFS1 | O76024 | wolframin ER transmembrane glycoprotein | 1.6E-38 | 0.528 | 0.846 | |
TBP | P20226 | TATA-box binding protein | Transcription factor | 1.5E-02 | 0.552 | 0.846 |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
SLC52A2 | Q9HAB3 | solute carrier family 52 member 2 | Transporter | 2.5E-03 | 0.483 | 0.808 |