Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846