Disease: Proliferative vitreoretinopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846