Disease: Abnormality of the skeletal system
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CYP26B1 Q9NR63 cytochrome P450 family 26 subfamily B member 1 Enzyme 0.98 0.666 0.500
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
FLNB O75369 filamin B 6.1E-10 0.458 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GNPTAB Q3T906 N-acetylglucosamine-1-phosphate transferase subunits alpha and beta 7.7E-19 0.592 0.731
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
LMX1B O60663 LIM homeobox transcription factor 1 beta Nucleic acid binding 0.75 0.565 0.731
MAB21L2 Q9Y586 mab-21 like 2 0.44 0.743 0.308
MAGEL2 Q9UJ55 MAGE family member L2 Cell adhesion 0.98 0.560 0.654
MATN1 P21941 matrilin 1 Receptor 2.6E-03 0.644 0.615
NAGLU P54802 N-acetyl-alpha-glucosaminidase 1.4E-08 0.546 0.769
NKX3-2 P78367 NK3 homeobox 2 Transcription factor 0.64 0.736 0.308
NPPC P23582 natriuretic peptide C Signaling 6.1E-02 0.568 0.769
POLR1C O15160 RNA polymerase I and III subunit C Enzyme 6.3E-10 0.595 0.615
POLR1D P0DPB5 P0DPB6 RNA polymerase I and III subunit D Enzyme 0.36 0.603 0.692
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PTH1R Q03431 parathyroid hormone 1 receptor G-protein coupled receptor 0.57 0.544 0.731