Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
ABL1 | P00519 | ABL proto-oncogene 1, non-receptor tyrosine kinase | Kinase | 1.00 | 0.432 | 0.923 |
GJA1 | P17302 | gap junction protein alpha 1 | Cell-cell junction | 0.16 | 0.393 | 0.885 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
FANCD2 | Q9BXW9 | FA complementation group D2 | 1.1E-30 | 0.479 | 0.885 | |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
ANK1 | P16157 | ankyrin 1 | 1.00 | 0.540 | 0.885 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
GATA4 | P43694 | GATA binding protein 4 | 0.49 | 0.458 | 0.846 | |
CDC42 | P60953 | cell division cycle 42 | Enzyme modulator | 0.79 | 0.458 | 0.846 |
ERCC4 | Q92889 | ERCC excision repair 4, endonuclease catalytic subunit | Enzyme | 1.4E-12 | 0.468 | 0.846 |
LIG4 | P49917 | DNA ligase 4 | 4.2E-06 | 0.478 | 0.846 | |
ARID1B | Q8NFD5 | AT-rich interaction domain 1B | 1.00 | 0.503 | 0.846 | |
DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | Enzyme | 3.9E-13 | 0.500 | 0.846 |
SMS | P52788 | spermine synthase | 0.97 | 0.491 | 0.846 | |
USP9X | Q93008 | ubiquitin specific peptidase 9 X-linked | 1.00 | 0.502 | 0.846 | |
DPYD | Q12882 | dihydropyrimidine dehydrogenase | Enzyme | 3.4E-22 | 0.493 | 0.846 |
EBP | Q15125 | EBP cholestenol delta-isomerase | Enzyme | 0.94 | 0.494 | 0.846 |
RERE | Q9P2R6 | arginine-glutamic acid dipeptide repeats | 1.00 | 0.526 | 0.846 | |
HNRNPK | P61978 | heterogeneous nuclear ribonucleoprotein K | Enzyme | 1.00 | 0.539 | 0.846 |