Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769