Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ATN1 P54259 atrophin 1 1.00 0.409 0.885
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846