Disease: Joint stiffness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DEAF1 O75398 DEAF1 transcription factor 3.4E-04 0.575 0.615
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FBN2 P35556 fibrillin 2 Calcium-binding protein 1.00 0.505 0.808
FLII Q13045 FLII actin remodeling protein 5.5E-12 0.520 0.808
GABRD O14764 gamma-aminobutyric acid type A receptor subunit delta Ion channel 0.99 0.558 0.692
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885
IQSEC2 Q5JU85 IQ motif and Sec7 domain ArfGEF 2 1.00 0.573 0.577
KCNAB2 Q13303 potassium voltage-gated channel subfamily A regulatory beta subunit 2 Ion channel 0.80 0.593 0.692
LEMD3 Q9Y2U8 LEM domain containing 3 1.00 0.582 0.731
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MYH3 P11055 myosin heavy chain 3 6.7E-21 0.563 0.654
NALCN Q8IZF0 sodium leak channel, non-selective Ion channel 8.5E-14 0.587 0.615
OCRL Q01968 OCRL inositol polyphosphate-5-phosphatase Enzyme 1.00 0.553 0.731
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
RAB3GAP1 Q15042 RAB3 GTPase activating protein catalytic subunit 1 1.5E-07 0.566 0.692
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846
SH3PXD2B A1X283 SH3 and PX domains 2B 4.2E-03 0.631 0.577
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808