Disease: Developmental Disabilities
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PUF60 Q9UHX1 poly(U) binding splicing factor 60 1.00 0.536 0.769
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIGA P37287 phosphatidylinositol glycan anchor biosynthesis class A 0.96 0.575 0.654
PAX6 P26367 paired box 6 1.00 0.450 0.769
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885
NR2F1 P10589 nuclear receptor subfamily 2 group F member 1 Nuclear receptor 0.99 0.656 0.654
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NDN Q99608 necdin, MAGE family member Nucleic acid binding 0.67 0.578 0.654
NANS Q9NR45 N-acetylneuraminate synthase Enzyme 0.545 0.692
NAA10 P41227 N-alpha-acetyltransferase 10, NatA catalytic subunit Enzyme 0.76 0.535 0.692
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885