Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
ANK1 P16157 ankyrin 1 1.00 0.540 0.885
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846