Disease: Hyperlipidemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423
DOCK7 Q96N67 dedicator of cytokinesis 7 Enzyme modulator 6.4E-06 0.682 0.423
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
F7 P08709 coagulation factor VII Enzyme 1.3E-05 0.623 0.615
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
PCSK7 Q16549 proprotein convertase subtilisin/kexin type 7 4.2E-03 0.631 0.615
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
ST3GAL4 Q11206 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 4.0E-02 0.588 0.692
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
PPARGC1B Q86YN6 PPARG coactivator 1 beta Transcription factor 0.50 0.569 0.731
SERPINC1 P01008 serpin family C member 1 Enzyme modulator 1.00 0.507 0.769
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769