Disease: Cholelithiasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARGC1B Q86YN6 PPARG coactivator 1 beta Transcription factor 0.50 0.569 0.731
SLC4A1 P02730 solute carrier family 4 member 1 (Diego blood group) Transporter 0.85 0.522 0.731
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
UGT1A10 Q9HAW8 UDP glucuronosyltransferase family 1 member A10 4.6E-19 0.588 0.615