Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
NGF | P01138 | nerve growth factor | Signaling | 0.82 | 0.391 | 0.885 |
MUC1 | P15941 | mucin 1, cell surface associated | 1.9E-02 | 0.384 | 0.885 | |
HSPA4 | P34932 | heat shock protein family A (Hsp70) member 4 | 1.00 | 0.394 | 0.923 | |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
ABO | P16442 | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | Enzyme | 0.427 | 0.885 | |
HLA-DQA1 | P01909 | major histocompatibility complex, class II, DQ alpha 1 | Immune response | 2.4E-02 | 0.416 | 0.846 |
APOA1 | P02647 | apolipoprotein A1 | 5.5E-04 | 0.429 | 0.885 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
TGFB2 | P61812 | transforming growth factor beta 2 | Signaling | 1.00 | 0.433 | 0.885 |
OPRM1 | P35372 | opioid receptor mu 1 | G-protein coupled receptor | 7.9E-11 | 0.457 | 0.808 |
PRKCA | P17252 | protein kinase C alpha | Kinase | 0.37 | 0.440 | 0.846 |
IGFBP3 | P17936 | insulin like growth factor binding protein 3 | Enzyme modulator | 0.91 | 0.439 | 0.808 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |