| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
| MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
| SCN1A | P35498 | sodium voltage-gated channel alpha subunit 1 | Ion channel | 1.00 | 0.477 | 0.808 |
| TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
| TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
| SCN1A-AS1 | SCN1A and SCN9A antisense RNA 1 | 0.636 | 0.346 | |||
| IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
| AKT3 | Q9Y243 | AKT serine/threonine kinase 3 | Kinase | 1.00 | 0.512 | 0.808 |
| DEPDC5 | O75140 | DEP domain containing 5, GATOR1 subcomplex subunit | Nucleic acid binding | 0.12 | 0.631 | 0.538 |
| RHEB | Q15382 | Ras homolog, mTORC1 binding | Enzyme modulator | 0.98 | 0.631 | 0.577 |