Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
RECQL4 | O94761 | RecQ like helicase 4 | Enzyme | 3.3E-35 | 0.496 | 0.808 |
MBTPS2 | O43462 | membrane bound transcription factor peptidase, site 2 | Enzyme | 1.00 | 0.513 | 0.769 |
TWIST2 | Q8WVJ9 | twist family bHLH transcription factor 2 | Transcription factor | 0.56 | 0.518 | 0.731 |
SMARCA2 | P51531 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | Epigenetic regulator | 1.00 | 0.527 | 0.769 |
MAP2K2 | P36507 | mitogen-activated protein kinase kinase 2 | Kinase | 0.97 | 0.534 | 0.731 |
EDA | Q92838 | ectodysplasin A | 0.97 | 0.553 | 0.808 | |
FRAS1 | Q86XX4 | Fraser extracellular matrix complex subunit 1 | 3.1E-45 | 0.560 | 0.577 | |
CDH3 | P22223 | cadherin 3 | 2.8E-10 | 0.560 | 0.615 | |
UBE3B | Q7Z3V4 | ubiquitin protein ligase E3B | 4.2E-08 | 0.590 | 0.692 | |
RIPK4 | P57078 | receptor interacting serine/threonine kinase 4 | Kinase | 4.0E-03 | 0.565 | 0.654 |
SOX18 | P35713 | SRY-box transcription factor 18 | Transcription factor | 0.15 | 0.578 | 0.692 |
TTC7A | Q9ULT0 | tetratricopeptide repeat domain 7A | 1.5E-31 | 0.641 | 0.577 | |
ALX1 | Q15699 | ALX homeobox 1 | 0.18 | 0.636 | 0.462 | |
UROS | P10746 | uroporphyrinogen III synthase | Enzyme | 3.2E-02 | 0.678 | 0.462 |
HR | O43593 | HR lysine demethylase and nuclear receptor corepressor | Transcription factor | 7.4E-10 | 0.722 | 0.192 |
KRT85 | P78386 | keratin 85 | 3.1E-06 | 0.751 | 0.115 |