Disease: High, narrow palate
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
ORC6 Q9Y5N6 origin recognition complex subunit 6 Nucleic acid binding 3.4E-07 0.628 0.577
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MUSK O15146 muscle associated receptor tyrosine kinase Kinase 4.2E-08 0.570 0.769
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
MAP3K7 O43318 mitogen-activated protein kinase kinase kinase 7 Kinase 1.00 0.477 0.808
CDK13 Q14004 cyclin dependent kinase 13 Kinase 0.91 0.606 0.692
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
FZD2 Q14332 frizzled class receptor 2 G-protein coupled receptor 0.65 0.558 0.654
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731
ATN1 P54259 atrophin 1 1.00 0.409 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
TCTN3 Q6NUS6 tectonic family member 3 4.2E-12 0.566 0.615