Disease: Low-set, posteriorly rotated ears
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769
TUBB P07437 tubulin beta class I Cellular structure 0.98 0.603 0.692
GNAI3 P08754 G protein subunit alpha i3 Enzyme modulator 3.8E-02 0.653 0.615
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
CD96 P40200 CD96 molecule 1.4E-11 0.592 0.692
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
PEX3 P56589 peroxisomal biogenesis factor 3 1.6E-02 0.595 0.731
PPP1CB P62140 protein phosphatase 1 catalytic subunit beta Enzyme 1.00 0.601 0.577
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
RBM10 P98175 RNA binding motif protein 10 1.00 0.599 0.615
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PLCB4 Q15147 phospholipase C beta 4 Enzyme 3.0E-06 0.610 0.731