Disease: 2-3 toe syndactyly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADNP Q9H2P0 activity dependent neuroprotector homeobox 1.00 0.561 0.808
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
DEAF1 O75398 DEAF1 transcription factor 3.4E-04 0.575 0.615
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
IL1RAPL1 Q9NZN1 interleukin 1 receptor accessory protein like 1 Receptor 1.00 0.617 0.692
MAN1B1 Q9UKM7 mannosidase alpha class 1B member 1 Chaperone 1.2E-08 0.606 0.577
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
MEIS2 O14770 Meis homeobox 2 Enzyme 1.00 0.601 0.808
PHF6 Q8IWS0 PHD finger protein 6 Nucleic acid binding 1.00 0.581 0.692
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PTCHD1 Q96NR3 patched domain containing 1 Receptor 0.98 0.678 0.385
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RBPJ Q06330 recombination signal binding protein for immunoglobulin kappa J region Nucleic acid binding 1.00 0.518 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOX5 P35711 SRY-box transcription factor 5 1.00 0.545 0.769
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577