Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DCR Down syndrome chromosome region 0.674 0.538
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
PAX1 P15863 paired box 1 0.70 0.593 0.654
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
HOXA13 P31271 homeobox A13 0.96 0.552 0.654
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
SLURP1 P55000 secreted LY6/PLAUR domain containing 1 0.26 0.560 0.654
RAP1B P61224 RAP1B, member of RAS oncogene family Enzyme modulator 0.91 0.565 0.769
RAP1A P62834 RAP1A, member of RAS oncogene family Enzyme modulator 0.62 0.502 0.808
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
DHODH Q02127 dihydroorotate dehydrogenase (quinone) Enzyme 3.0E-03 0.576 0.769
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923