Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DCR Down syndrome chromosome region 0.674 0.538
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
ELN P15502 elastin 2.1E-14 0.415 0.885
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
SLC25A24 Q6NUK1 solute carrier family 25 member 24 Transporter 3.4E-12 0.575 0.731
PIGL Q9Y2B2 phosphatidylinositol glycan anchor biosynthesis class L 6.2E-09 0.581 0.731
RAB3GAP1 Q15042 RAB3 GTPase activating protein catalytic subunit 1 1.5E-07 0.566 0.692
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
TBL2 Q9Y4P3 transducin beta like 2 1.8E-04 0.538 0.731
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
DHODH Q02127 dihydroorotate dehydrogenase (quinone) Enzyme 3.0E-03 0.576 0.769
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
SLURP1 P55000 secreted LY6/PLAUR domain containing 1 0.26 0.560 0.654
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RAP1A P62834 RAP1A, member of RAS oncogene family Enzyme modulator 0.62 0.502 0.808
PAX1 P15863 paired box 1 0.70 0.593 0.654
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769
RAP1B P61224 RAP1B, member of RAS oncogene family Enzyme modulator 0.91 0.565 0.769
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731