Disease: Progressive sensorineural hearing impairment
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTG1 P63261 actin gamma 1 Cellular structure 4.8E-03 0.477 0.846
ATP6V0A4 Q9HBG4 ATPase H+ transporting V0 subunit a4 Transporter 2.2E-20 0.722 0.385
ATP6V1B1 P15313 ATPase H+ transporting V1 subunit B1 Transporter 2.4E-09 0.695 0.346
COCH O43405 cochlin Receptor 1.2E-07 0.659 0.385
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX3 P00414 cytochrome c oxidase III Enzyme 0.546 0.808
CYTB P00156 cytochrome b 0.529 0.808
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
GSDME O60443 gasdermin E 3.3E-09 0.656 0.423
IARS2 Q9NSE4 isoleucyl-tRNA synthetase 2, mitochondrial Enzyme 8.1E-02 0.590 0.654
MYH14 Q7Z406 myosin heavy chain 14 4.2E-02 0.663 0.577
MYO15A Q9UKN7 myosin XVA Cellular structure 1.3E-56 0.722 0.346
MYO3A Q8NEV4 myosin IIIA Kinase 1.8E-45 0.780 0.269
MYO6 Q9UM54 myosin VI Cellular structure 2.4E-05 0.631 0.731
MYO7A Q13402 myosin VIIA Cellular structure 1.6E-38 0.585 0.423
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
POU3F4 P49335 POU class 3 homeobox 4 0.57 0.633 0.654
TECTA O75443 tectorin alpha 3.0E-16 0.700 0.385
TMC1 Q8TDI8 transmembrane channel like 1 Ion channel 9.2E-19 0.769 0.346
TPRN Q4KMQ1 taperin 7.2E-03 0.839 0.115