Disease: Leber Congenital Amaurosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA4 P78363 ATP binding cassette subfamily A member 4 Transporter 5.3E-48 0.493 0.769
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
AIPL1 Q9NZN9 aryl hydrocarbon receptor interacting protein like 1 Chaperone 1.2E-05 0.644 0.346
CDHR1 Q96JP9 cadherin related family member 1 2.8E-21 0.670 0.308
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
CLTA P09496 clathrin light chain A Transporter 0.96 0.628 0.654
CNGA3 Q16281 cyclic nucleotide gated channel subunit alpha 3 Ion channel 8.0E-20 0.650 0.154
CNTLN Q9NXG0 centlein 4.0E-49 0.805 0.269
CRB1 P82279 crumbs cell polarity complex component 1 5.6E-16 0.570 0.654
CRB2 Q5IJ48 crumbs cell polarity complex component 2 1.5E-14 0.678 0.269
CRX O43186 cone-rod homeobox Transcription factor 0.51 0.565 0.692
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
GUCA1A P43080 guanylate cyclase activator 1A 4.1E-04 0.647 0.500
GUCA1B Q9UMX6 guanylate cyclase activator 1B 2.1E-04 0.682 0.423
GUCY2D Q02846 guanylate cyclase 2D, retinal Kinase 6.5E-10 0.570 0.769
IFT140 Q96RY7 intraflagellar transport 140 Cellular structure 9.9E-24 0.572 0.692
IMPDH1 P20839 inosine monophosphate dehydrogenase 1 Enzyme 5.8E-06 0.623 0.462
IMPG2 Q9BZV3 interphotoreceptor matrix proteoglycan 2 Extracellular structure 2.8E-13 0.659 0.308
IQCB1 Q15051 IQ motif containing B1 1.4E-12 0.641 0.654
KCNJ13 O60928 potassium inwardly rectifying channel subfamily J member 13 Ion channel 1.4E-02 0.659 0.308
LCA5 Q86VQ0 lebercilin LCA5 4.1E-05 0.674 0.269
LRAT O95237 lecithin retinol acyltransferase 2.8E-02 0.608 0.654
MERTK Q12866 MER proto-oncogene, tyrosine kinase Kinase 2.7E-11 0.531 0.692
MYO7A Q13402 myosin VIIA Cellular structure 1.6E-38 0.585 0.423
NMNAT1 Q9HAN9 nicotinamide nucleotide adenylyltransferase 1 Enzyme 3.5E-02 0.656 0.269