Disease: Multiple congenital anomalies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SHOC2 Q9UQ13 SHOC2 leucine rich repeat scaffold protein 1.00 0.593 0.769
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769
DLL4 Q9NR61 delta like canonical Notch ligand 4 1.00 0.494 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
ALX4 Q9H161 ALX homeobox 4 0.36 0.560 0.692
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
NHS Q6T4R5 NHS actin remodeling regulator 1.00 0.466 0.846
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
BMP7 P18075 bone morphogenetic protein 7 Signaling 0.13 0.498 0.769
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846