Disease: Primary malignant neoplasm of brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DTX2 Q86UW9 deltex E3 ubiquitin ligase 2 Enzyme 2.9E-02 0.792 0.077
IQGAP2 Q13576 IQ motif containing GTPase activating protein 2 Enzyme modulator 8.5E-27 0.674 0.269
NRARP Q7Z6K4 NOTCH regulated ankyrin repeat protein 0.21 0.722 0.308
FJX1 Q86VR8 four-jointed box kinase 1 0.94 0.705 0.462
AMOT Q4VCS5 angiomotin 1.00 0.641 0.538
EML4 Q9HC35 EMAP like 4 4.8E-04 0.569 0.577
HES5 Q5TA89 hes family bHLH transcription factor 5 0.25 0.670 0.654
IQGAP1 P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 1.00 0.560 0.692
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CYP2C9 P11712 cytochrome P450 family 2 subfamily C member 9 1.3E-10 0.506 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885