BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
ERCC6 |
P0DP91 Q03468
|
ERCC excision repair 6, chromatin remodeling factor
|
|
5.2E-22 |
0.507 |
0.808 |
PMS1 |
P54277
|
PMS1 homolog 1, mismatch repair system component
|
Nucleic acid binding
|
1.3E-17 |
0.569 |
0.654 |
ERCC4 |
Q92889
|
ERCC excision repair 4, endonuclease catalytic subunit
|
Enzyme
|
1.4E-12 |
0.468 |
0.846 |
ATR |
Q13535
|
ATR serine/threonine kinase
|
Kinase
|
3.5E-09 |
0.456 |
0.923 |
MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
OPCML |
Q14982
|
opioid binding protein/cell adhesion molecule like
|
|
0.23 |
0.606 |
0.654 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
AKT2 |
P31751
|
AKT serine/threonine kinase 2
|
Kinase
|
0.64 |
0.474 |
0.769 |
RNF43 |
Q68DV7
|
ring finger protein 43
|
|
0.73 |
0.584 |
0.577 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
CCNE1 |
P24864
|
cyclin E1
|
Enzyme modulator
|
0.97 |
0.538 |
0.731 |
RRAS2 |
P62070
|
RAS related 2
|
Enzyme modulator
|
0.97 |
0.656 |
0.500 |
AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |