Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
FGF3 P11487 fibroblast growth factor 3 Signaling 9.3E-05 0.505 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
FGF4 P08620 fibroblast growth factor 4 Signaling 0.14 0.588 0.577
FOXA1 P55317 forkhead box A1 Transcription factor 0.22 0.522 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
INPP4B O15327 inositol polyphosphate-4-phosphatase type II B 0.55 0.573 0.577
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
MAP3K13 O43283 mitogen-activated protein kinase kinase kinase 13 Kinase 0.80 0.743 0.192
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808
TBX3 O15119 T-box transcription factor 3 Transcription factor 0.99 0.525 0.769
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846