Disease: Mild Mental Retardation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PTCH1 Q13635 patched 1 1.00 0.398 0.885
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
DMD P11532 dystrophin 1.00 0.423 0.923
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
DAG1 Q14118 dystroglycan 1 Receptor 0.98 0.498 0.808