Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
SIRT1 | Q96EB6 | sirtuin 1 | Epigenetic regulator | 8.7E-02 | 0.378 | 0.885 |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
HSPB1 | P04792 | heat shock protein family B (small) member 1 | 2.8E-07 | 0.436 | 0.808 | |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
ATP7A | Q04656 | ATPase copper transporting alpha | Transporter | 1.00 | 0.494 | 0.769 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
PMP22 | Q01453 | peripheral myelin protein 22 | Cellular structure | 0.91 | 0.471 | 0.885 |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
CD59 | P13987 | CD59 molecule (CD59 blood group) | 0.61 | 0.469 | 0.808 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
SLC12A3 | P55017 | solute carrier family 12 member 3 | Transporter | 3.0E-32 | 0.493 | 0.808 |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 |