Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
INS P01308 insulin 0.30 0.445 0.923
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
VCP P55072 valosin containing protein 1.00 0.469 0.923
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769