Disease: Familial (FPAH)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
NEFL P07196 neurofilament light 0.488 0.769
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
DNAJB1P1 DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 0.650 0.654
MIR137 microRNA 137 0.513 0.846
MIR155 microRNA 155 0.384 0.885
MIR21 microRNA 21 0.363 0.846
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
PGR-AS1 PGR antisense RNA 1 0.514 0.808
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
TRPM2 O94759 transient receptor potential cation channel subfamily M member 2 Ion channel 9.0E-44 0.546 0.731
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
GPNMB Q14956 glycoprotein nmb Signaling 2.9E-27 0.566 0.692
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
PTPN13 Q12923 protein tyrosine phosphatase non-receptor type 13 1.4E-25 0.592 0.654
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
EPHA1 P21709 EPH receptor A1 Kinase 1.5E-23 0.544 0.731