Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MS multiple sclerosis 0.599 0.692
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
PANK2 Q9BZ23 pantothenate kinase 2 Kinase 7.4E-07 0.559 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885
SMN1 Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 1.6E-02 0.454 0.769
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
RETN Q9HD89 resistin 3.7E-02 0.454 0.808