Disease: Cerebellar Ataxia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EIF2B4 Q9UI10 eukaryotic translation initiation factor 2B subunit delta 0.96 0.659 0.538
ATXN7 O15265 ataxin 7 0.96 0.581 0.654
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
EIF2S2 P20042 eukaryotic translation initiation factor 2 subunit beta Nucleic acid binding 0.95 0.621 0.577
HMBS P08397 hydroxymethylbilane synthase Enzyme 0.95 0.559 0.731
FGF9 P31371 fibroblast growth factor 9 Signaling 0.95 0.528 0.846
RPS4X P62701 ribosomal protein S4 X-linked Nucleic acid binding 0.93 0.711 0.500
RPSA P08865 ribosomal protein SA Nucleic acid binding 0.93 0.485 0.769
USP14 P54578 ubiquitin specific peptidase 14 Enzyme 0.91 0.595 0.654
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
DENR O43583 density regulated re-initiation and release factor Enzyme 0.88 0.543 0.692
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
NOP56 O00567 NOP56 ribonucleoprotein Nucleic acid binding 0.62 0.663 0.538
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
OPA3 Q9H6K4 outer mitochondrial membrane lipid metabolism regulator OPA3 0.57 0.653 0.385
LMNB1 P20700 lamin B1 0.55 0.564 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962