Disease: Complex partial seizures
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
ADRA1B P35368 adrenoceptor alpha 1B G-protein coupled receptor 0.14 0.686 0.500
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
GABRA5 P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 0.91 0.621 0.385
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846
SLC12A5 Q9H2X9 solute carrier family 12 member 5 Transporter 1.00 0.570 0.654