Disease: Absence of secondary sex characteristics
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LHX4 Q969G2 LIM homeobox 4 Nucleic acid binding 1.8E-02 0.621 0.462
HSD3B2 P26439 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Enzyme 7.2E-08 0.582 0.500
DMRT3 Q9NQL9 doublesex and mab-3 related transcription factor 3 6.2E-06 0.653 0.500
VAMP7 P51809 vesicle associated membrane protein 7 Transporter 1.4E-02 0.612 0.577
PROP1 O75360 PROP paired-like homeobox 1 8.8E-02 0.576 0.615
CYB5A P00167 cytochrome b5 type A Enzyme 1.6E-03 0.601 0.654
GNRHR P30968 gonadotropin releasing hormone receptor G-protein coupled receptor 6.8E-02 0.540 0.654
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
HESX1 Q9UBX0 HESX homeobox 1 8.0E-04 0.561 0.654
FGF17 O60258 fibroblast growth factor 17 Signaling 0.96 0.593 0.692
NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor 0.26 0.606 0.692
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
GNRH1 P01148 gonadotropin releasing hormone 1 0.15 0.524 0.731
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
SOX3 P41225 SRY-box transcription factor 3 Transcription factor 0.45 0.535 0.731
TAC3 Q9UHF0 tachykinin precursor 3 1.2E-02 0.604 0.731
HS6ST1 O60243 heparan sulfate 6-O-sulfotransferase 1 Enzyme 0.92 0.617 0.731
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731
PROKR2 Q8NFJ6 prokineticin receptor 2 G-protein coupled receptor 2.4E-06 0.538 0.731
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
ANOS1 P23352 anosmin 1 1.00 0.537 0.769
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769