Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846