Disease: Tumor Initiation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
PAG1 Q9NWQ8 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 1.8E-02 0.505 0.808
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
LPAR2 Q9HBW0 lysophosphatidic acid receptor 2 G-protein coupled receptor 3.7E-02 0.463 0.846
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
FOXC2 Q99958 forkhead box C2 Transcription factor 0.13 0.515 0.731
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
PARD3 Q8TEW0 par-3 family cell polarity regulator 0.96 0.608 0.615
SFRP1 Q8N474 secreted frizzled related protein 1 0.96 0.479 0.846
LAMA3 Q16787 laminin subunit alpha 3 Enzyme modulator 8.8E-46 0.576 0.731
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
NEDD8 Q15843 NEDD8 ubiquitin like modifier Nucleic acid binding 0.85 0.576 0.692
PDK1 Q15118 pyruvate dehydrogenase kinase 1 Kinase 1.1E-05 0.510 0.808
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
LAMB3 Q13751 laminin subunit beta 3 Enzyme modulator 2.3E-15 0.558 0.692
PTCH1 Q13635 patched 1 1.00 0.398 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808