Disease: Optic Atrophy
Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND2 P03891 MTND2 0.601 0.615
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
TRNN tRNA 0.682 0.577
TRNS1 tRNA 0.555 0.808
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
TUBGCP6 Q96RT7 tubulin gamma complex associated protein 6 Cellular structure 2.6E-31 0.695 0.308
RPGRIP1L Q68CZ1 RPGRIP1 like Enzyme modulator 4.1E-31 0.534 0.769
FCSK Q8N0W3 fucose kinase Kinase 1.0E-29 0.769 0.192
CSPP1 Q1MSJ5 centrosome and spindle pole associated protein 1 3.3E-29 0.544 0.769
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692
EMC1 Q8N766 ER membrane protein complex subunit 1 6.7E-26 0.700 0.462
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
IFT140 Q96RY7 intraflagellar transport 140 Cellular structure 9.9E-24 0.572 0.692
RPGRIP1 Q96KN7 RPGR interacting protein 1 Enzyme modulator 1.3E-23 0.553 0.654
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
MMUT P22033 methylmalonyl-CoA mutase Enzyme 1.7E-22 0.534 0.731
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
POMGNT1 Q8WZA1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.9E-20 0.537 0.538
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615