Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885
MAP6 Q96JE9 microtubule associated protein 6 0.40 0.578 0.769
MGLL Q99685 monoglyceride lipase Enzyme 2.0E-02 0.564 0.731
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962