Disease: Muscle Weakness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRNK tRNA 0.608 0.577
LAMA2 P24043 laminin subunit alpha 2 Enzyme modulator 2.4E-47 0.553 0.692
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
CPLANE1 Q9H799 ciliogenesis and planar polarity effector 1 5.9E-36 0.575 0.692
CCDC141 Q6ZP82 coiled-coil domain containing 141 1.6E-33 0.666 0.538
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
MYH3 P11055 myosin heavy chain 3 6.7E-21 0.563 0.654
POMGNT1 Q8WZA1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.9E-20 0.537 0.538
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
CAPN3 P20807 calpain 3 Enzyme 3.6E-19 0.564 0.615
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769
POMT1 Q9Y6A1 protein O-mannosyltransferase 1 4.2E-17 0.525 0.615
GNE Q9Y223 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Enzyme 2.5E-16 0.610 0.692
IGHMBP2 P38935 immunoglobulin mu DNA binding protein 2 3.0E-16 0.636 0.615
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654
ASAH1 Q13510 N-acylsphingosine amidohydrolase 1 Enzyme 1.3E-12 0.526 0.808
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
POMT2 Q9UKY4 protein O-mannosyltransferase 2 9.4E-12 0.544 0.615
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
MSTO1 Q9BUK6 misato mitochondrial distribution and morphology regulator 1 1.6E-09 0.582 0.692