Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SOCS3 O14543 suppressor of cytokine signaling 3 Enzyme modulator 0.75 0.434 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
WAS P42768 WASP actin nucleation promoting factor Cellular structure 1.00 0.529 0.808
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
MIR451A microRNA 451a 0.505 0.769
ANO1 Q5XXA6 anoctamin 1 Ion channel 0.87 0.516 0.769
MIR144 microRNA 144 0.500 0.769
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
P2RY12 Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 1.7E-03 0.533 0.731
MIR34C microRNA 34c 0.541 0.885
MGLL Q99685 monoglyceride lipase Enzyme 2.0E-02 0.564 0.731
DDX53 Q86TM3 DEAD-box helicase 53 0.66 0.568 0.846
VDAC1 P21796 voltage dependent anion channel 1 0.97 0.556 0.654
MAP6 Q96JE9 microtubule associated protein 6 0.40 0.578 0.769